ISMRM 2016 was an exciting one for our group, as student Kimberly Chan presented HERMES: Hadamard-Encoding and Reconstruction of MEGA-Edited Spectroscopy.
HERMES: Coming to a journal near you in the very near future.
In principle, HERMES allows the orthogonal encoding of an arbitrary number of edited metabolites in a single acquisition. Rather than jettisoning all the 'other' signals as with MEGA editing, HERMES can put them into a second difference spectrum, or a third, or...