Saipavitra (Pavi) Murali Manohar, PhD

Biography:

Pavi received her BSc (Hons.) degree in physics from Sri Sathya Sai Institute of Higher Learning, India. After completing her MSc in physics from National Institute of Technology in Trichy, India, she went on to pursue her PhD at Max Planck Institute for Biological Cybernetics in Tübingen, Germany under the supervision of Dr. Anke Henning. Pavi’s doctoral thesis was on quantifying human brain metabolites and macromolecules using magnetic resonance spectroscopy (MRS) at ultra-high field. During her PhD, she measured the T1 and T2 relaxation times of metabolites and macromolecules in the human brain at 9.4 T. Her other focuses were development of two-dimensional J-resolved sequence, and labeling of downfield peaks in the proton MR spectra.

Pavi is now a postdoctoral fellow in Richard Edden’s group at the Johns Hopkins University. Her current research focus continues to be in MRS. She is also working on sequence development of the edited MRS pulse sequences enabling researchers to focus on low concentration metabolites, including GABA, glutamate, Glutathione, and more. Quantifying these metabolites helps us understand neurotransmission and neurochemical changes in the human brain with aging and several neuro pathologies.

Contact:

svenka23 [at] jhmi [dot] edu